Description

4-Fluorobenzoylacetonitrile is a versatile fluorinated organic building block, specifically a β-ketonitrile derivative. This compound is highly valued in advanced organic synthesis for its dual reactive sites, enabling the construction of complex heterocyclic and pharmaceutical intermediates. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated heterocycles, such as pyrazoles and pyrimidines, which are core structures in various active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used to develop novel fluorinated pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Building block for synthesizing advanced organic electronic materials and fluorinated polymers with unique properties.
• Chemical Research & Development: A versatile reagent for method development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	4-Fluorobenzoylacetonitrile
CAS No.	4640-67-9
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	4-Fluorobenzoylacetonitrile; 3-Oxo-3-(4-fluorophenyl)propanenitrile; 4-Fluorobenzoylmethyl cyanide; 1-(4-Fluorophenyl)-1,3-butanedione-3-carbonitrile; 4-Fluorobenzoyl methyl nitrile; p-Fluorobenzoylacetonitrile; 4-Fluorophenyl 3-oxopropanenitrile; (4-Fluorobenzoyl)acetonitrile
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzoylacetonitrile is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting research and production standards. A detailed Certificate of Analysis (COA) with batch-specific data is provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.