Description

2-Bromo-1-(2,5-Dichlorophenyl)Ethanone is a versatile and highly reactive bromoketone building block, essential for advanced organic synthesis. Its precise molecular structure, featuring both bromine and chlorine substituents, makes it a critical intermediate for constructing complex heterocyclic and pharmaceutical scaffolds. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the 2,5-dichlorophenyl moiety is required.
• Organic Synthesis Building Block: Serves as a versatile electrophile in Friedel-Crafts acylation, Suzuki-Miyaura, and other palladium-catalyzed cross-coupling reactions.
• Heterocyclic Chemistry: Fundamental starting material for the construction of various nitrogen- and oxygen-containing heterocycles, such as benzofurans and indoles.
• Material Science Research: Investigated as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Potential use in the development of activity-based probes (ABPs) and other biochemical tools due to its reactive carbonyl and halogen groups.

Basic Information

Product Name	2-Bromo-1-(2,5-Dichlorophenyl)Ethanone
CAS No.	4571-25-9
Molecular Formula	C8H5BrCl2O
Molecular Weight	268.94 g/mol
Synonyms	2-Bromo-2',5'-dichloroacetophenone; 2-Bromo-1-(2,5-dichlorophenyl)ethan-1-one; α-Bromo-2,5-dichloroacetophenone; Phenacyl bromide, 2',5'-dichloro-; 1-(2,5-Dichlorophenyl)-2-bromoethanone; 2',5'-Dichlorophenacyl bromide; NSC 403107
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-1-(2,5-Dichlorophenyl)Ethanone is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.