Description

(3,4-Dihydro-2H-Pyran-2-Yl)Methyl Methacrylate CAS NO 4563-45-5 is a specialized methacrylate monomer featuring a tetrahydropyranyl (THP) protecting group. This compound is a critical building block in organic synthesis, valued for its ability to introduce a polymerizable methacrylate moiety while offering a protecting group that can be cleaved under mild acidic conditions. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced polymer sectors for developing novel drug candidates, specialty coatings, and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), where the THP group protects alcohol functionalities during multi-step synthetic sequences.
• Polymer Chemistry & Material Science: Serves as a functional monomer for creating specialty polymers with tailored properties, such as stimuli-responsive coatings or hydrogels for controlled release applications.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, providing a versatile handle for molecular modification.
• Cross-linking Agent: Employed in the formulation of advanced adhesives, sealants, and composite materials to introduce specific cross-linking sites.
• Organic Synthesis Reagent: A versatile building block in academic and industrial R&D labs for constructing complex molecular architectures.
• Surface Modification: Used to graft polymer brushes onto surfaces for creating bio-compatible or functional interfaces in medical devices and sensors.

Basic Information

Item	Detail
Product Name	(3,4-Dihydro-2H-Pyran-2-Yl)Methyl Methacrylate
CAS No.	4563-45-5
Molecular Formula	C10H14O3
Molecular Weight	182.22 g/mol
Synonyms	2-((3,4-Dihydro-2H-pyran-2-yl)methoxy)-2-methylacrylic acid; THP-Methacrylate; Methacrylic acid (3,4-dihydro-2H-pyran-2-yl)methyl ester; 2-(Tetrahydropyran-2-yloxymethyl)prop-2-enoic acid methyl ester; (Tetrahydro-2H-pyran-2-yl)methyl methacrylate; 2-((Tetrahydro-2H-pyran-2-yl)methoxy)-2-methylacrylic acid; 4563-45-5; THP protected methacrylate
EINECS	Contact for details

Quality Control

Our (3,4-Dihydro-2H-Pyran-2-Yl)Methyl Methacrylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen) to prevent oxidation and polymerization. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.