Description

2-(Benzyloxycarbonylamino)Ethylboronic Acid is a versatile and valuable organoboron building block used in modern synthetic chemistry. This compound is particularly significant for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for carbon-carbon bond formation. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for coupling reactions to create complex molecular architectures.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds with aryl or vinyl halides, critical for constructing biaryl and other conjugated systems in medicinal chemistry.
• Peptidomimetic Research: Used in the development of peptide analogs and protease inhibitors by incorporating boron-containing functional groups.
• Agrochemical Synthesis: Serves as an intermediate in creating new generations of herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized to create boron-based probes for studying enzyme activity and protein interactions.

Basic Information

Product Name	2-(Benzyloxycarbonylamino)Ethylboronic Acid
CAS No.	4540-87-8
Molecular Formula	C₁₀H₁₄BNO₄
Molecular Weight	223.04 g/mol
Synonyms	N-Cbz-2-aminoethylboronic acid; (2-(((Benzyloxy)carbonyl)amino)ethyl)boronic acid; Z-AEBA; Cbz-NH-CH2-CH2-B(OH)2; 2-[(Benzyloxycarbonyl)amino]ethylboronic acid; B-[2-[[(Phenylmethoxy)carbonyl]amino]ethyl]boronic acid; N-α-Cbz-2-aminoethylboronic acid; Boronic acid, B-[2-[[(phenylmethoxy)carbonyl]amino]ethyl]-
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxycarbonylamino)Ethylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.