Description

1-Chloro-2-Fluorocyclohexane is a halogenated cycloalkane building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of chlorine and fluorine atoms on the cyclohexane ring, enabling precise molecular modifications. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly where the introduction of fluorine atoms is desired to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the halogenated structure for targeted biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex molecules, including natural product analogs and specialty chemicals.
• Material Science Research: Investigated as a precursor or modifier in the development of specialty polymers and liquid crystals with unique properties.
• Fluorination Chemistry Studies: Acts as a model substrate in methodological development for selective fluorination and subsequent functional group transformations.

Basic Information

Product Name	1-Chloro-2-Fluorocyclohexane
CAS No.	4536-11-2
Molecular Formula	C6H10ClF
Molecular Weight	136.60 g/mol
Synonyms	2-Fluoro-1-chlorocyclohexane; Cyclohexane, 1-chloro-2-fluoro-; 1-Chloro-2-fluorocyclohexane; 1-Chloro-2-fluoro-cyclohexane; 2-Fluorocyclohexyl chloride; (1s,2r)-1-chloro-2-fluorocyclohexane; (1r,2s)-1-chloro-2-fluorocyclohexane
EINECS	Contact for details

Quality Control

Our 1-Chloro-2-Fluorocyclohexane is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-8°C for extended stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Density	~1.1 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.