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n-Fluoroacetyl-D-Glucosamine CAS NO 4495-81-2


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CAS No.:4495-81-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Fluoroacetyl-D-Glucosamine is a fluorinated derivative of the fundamental amino sugar, D-glucosamine. This compound is a critical building block and intermediate in the synthesis of complex glycoconjugates and fluorinated carbohydrate analogs for advanced research. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and chemical synthesis sectors who require high-purity, specialized carbohydrate intermediates for drug discovery, probe development, and metabolic studies.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluorinated glycosides, nucleoside analogs, and glycopeptide antibiotics for drug discovery programs.
  • Biochemical Probe Synthesis: Used to create fluorinated carbohydrate probes for studying enzyme mechanisms, metabolic pathways, and glycosylation processes.
  • Glycoconjugate Research: Serves as a building block for the chemical and enzymatic synthesis of complex, fluorinated oligosaccharides and glycoconjugates.
  • Radiopharmaceutical Precursor: Potential intermediate in the development of 18F-labeled tracers for Positron Emission Tomography (PET) imaging.
  • Chemical Biology Tool: Enables the introduction of fluorine atoms into carbohydrate scaffolds to modulate their biological activity, stability, and binding properties.
  • Standards and Reference Material: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name n-Fluoroacetyl-D-Glucosamine
CAS No. 4495-81-2
Molecular Formula C8H14FNO6
Molecular Weight 239.20 g/mol
Synonyms 2-(Fluoroacetamido)-2-deoxy-D-glucose; N-Fluoroacetylglucosamine; 2-Deoxy-2-(fluoroacetamido)-D-glucopyranose; D-Glucosamine, N-fluoroacetyl-; Fluoroacetyl-D-glucosamine; N-FAG; 2-Acetamido-2-deoxy-D-glucose, N-fluoro-
EINECS Contact for details

Quality Control

Our n-Fluoroacetyl-D-Glucosamine is manufactured under a quality management system and undergoes rigorous analytical testing to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support development projects with material meeting research-grade specifications and scale up to current Good Manufacturing Practice (cGMP) standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Specific Rotation Contact for details
Heavy Metals < 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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