Description

4-Hydroxy-3-Methoxyphenylacetonitrile is a versatile aromatic nitrile derivative that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in its bifunctional structure, featuring both a phenolic hydroxyl and a nitrile group, which enables its use in constructing complex molecules for high-value applications. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for neurological and cardiovascular therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators, leveraging its aromatic core for bioactive molecule design.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers where the methoxyphenol structure imparts specific properties.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing complex aroma chemicals and vanillin derivatives.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and novel compound libraries.
• Material Science: Investigated for use in creating advanced organic electronic materials and liquid crystals.

Basic Information

Product Name	4-Hydroxy-3-Methoxyphenylacetonitrile
CAS No.	4468-59-1
Molecular Formula	C9H9NO2
Molecular Weight	163.17 g/mol
Synonyms	Vanillyl cyanide; 4-Hydroxy-3-methoxybenzyl cyanide; (4-Hydroxy-3-methoxyphenyl)acetonitrile; 2-(4-Hydroxy-3-methoxyphenyl)acetonitrile; Homovanillonitrile; 3-Methoxy-4-hydroxybenzyl cyanide; Vanillin acetonitrile; NSC 403697
EINECS	224-719-5

Quality Control

Our 4-Hydroxy-3-Methoxyphenylacetonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.