Description

2-(4-Chlorophenyl)-2-Hydroxypropionic Acid is a versatile organic acid derivative characterized by its chlorophenyl and hydroxypropionic acid functional groups. This compound serves as a critical chiral building block and intermediate in the synthesis of high-value fine chemicals and active pharmaceutical ingredients (APIs). It is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific biological activity.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Building block for the production of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Used in the development of advanced electronic display components and organic light-emitting diodes.
• Fine Chemical Production: Intermediate for creating complex molecules used in flavors, fragrances, and advanced polymers.
• Research & Development: Valuable reagent for academic and industrial research in organic chemistry and medicinal chemistry.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective chemical reactions.

Basic Information

Product Name	2-(4-Chlorophenyl)-2-Hydroxypropionic Acid
CAS No.	4445-13-0
Molecular Formula	C9H9ClO3
Molecular Weight	200.62 g/mol
Synonyms	p-Chloromandelic Acid; 2-Hydroxy-2-(4-chlorophenyl)propanoic Acid; (RS)-2-(4-Chlorophenyl)-2-hydroxypropionic Acid; 4-Chloro-α-hydroxybenzenepropanoic Acid; DL-p-Chloromandelic Acid; (±)-2-(4-Chlorophenyl)-2-hydroxypropionic Acid; 2-(4-Chlorophenyl)lactic Acid (common misnomer); α-Hydroxy-4-chlorohydrocinnamic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-2-Hydroxypropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. Due to its acidic nature, ensure storage containers are made of compatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118°C - 122°C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Optical Purity (Chiral HPLC)	Specified upon request (Racemic or Enantiopure grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.