Description

2(3H)-Benzofuranone, 3-Ethylidene- is a versatile heterocyclic organic compound, specifically a substituted benzofuranone, with the CAS registry number 4412-04-8. This specialized intermediate is valued for its unique molecular scaffold, which serves as a critical building block in the synthesis of complex molecules for advanced research and industrial applications. It is primarily sought by the pharmaceutical, agrochemical, and fine chemical industries for use in developing active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where its benzofuranone core contributes to biological activity.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and other performance chemicals requiring specific optical or electronic properties.
• Material Science Research: Investigated as a monomer or building block for novel polymers, liquid crystals, and organic electronic materials.
• Academic & R&D Laboratories: Employed in organic synthesis and methodological studies for constructing complex oxygen-containing heterocycles.

Basic Information

Product Name	2(3H)-Benzofuranone, 3-Ethylidene-
CAS No.	4412-04-8
Molecular Formula	C10H8O2
Molecular Weight	160.17 g/mol
Synonyms	3-Ethylidene-2(3H)-benzofuranone; 3-Ethylidenephthalide; 3-Ethyliden-2-benzofuran-1(3H)-one; 3-Ethylidene-1(3H)-isobenzofuranone; NSC 163022; Ethylidenephthalide; 3-Ethyliden-1-oxophthalan
EINECS	224-562-7

Quality Control

Our production of 2(3H)-Benzofuranone, 3-Ethylidene- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Specified range
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.