Description

1-Bromo-4-(1,3-Dioxolan-2-Ylmethyl)Benzene is a versatile aromatic bromo compound featuring a protected aldehyde functionality, making it a valuable synthetic intermediate in advanced organic chemistry. Its core value lies in its dual reactivity, where the bromine atom enables cross-coupling reactions and the acetal-protected aldehyde group serves as a masked carbonyl for subsequent transformations. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring aryl-bromide or protected aldehyde moieties.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as monomers for conjugated polymers.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fine Chemical Production: Intermediate for manufacturing dyes, flavors, and fragrances.

Basic Information

Product Name	1-Bromo-4-(1,3-Dioxolan-2-Ylmethyl)Benzene
CAS No.	4410-16-6
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	2-[(4-Bromophenyl)methyl]-1,3-dioxolane; 4-Bromobenzaldehyde Ethylene Acetal; (4-Bromobenzylidene)acetaldehyde Cyclic Ethylene Acetal; p-Bromobenzaldehyde Ethylene Acetal; 1-Bromo-4-(1,3-dioxolan-2-ylmethyl)benzene; 4-Bromobenzaldehyde Cyclic Ethylene Acetal; α-(4-Bromophenyl)-1,3-dioxolane-2-methane
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-(1,3-Dioxolan-2-Ylmethyl)Benzene is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR and NMR), and impurity profile is provided and available upon request, supporting your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.