Description

2,2'-Methylenebis[1,3-Dioxolane] is a high-purity specialty chemical building block, primarily utilized as a protected form of malondialdehyde. Its value lies in its role as a versatile precursor and protecting group in sophisticated organic synthesis, enabling the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over molecular structure is critical.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of heterocyclic compounds, nucleoside analogs, and complex active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides requiring specific cyclic acetal functionalities.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for the development of specialty polymers with tailored properties.
• Organic Synthesis Reagent: Acts as a protected dialdehyde equivalent in multi-step synthesis, including aldol and condensation reactions.
• Material Science Research: Employed in the development of novel organic frameworks and functional materials.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing specific aroma chemicals.

Basic Information

Product Name	2,2'-Methylenebis[1,3-Dioxolane]
CAS No.	4405-17-8
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	Malondialdehyde Bis(dimethyl acetal); 1,1,3,3-Tetramethoxypropane; Malonaldehyde Tetramethyl Acetal; Malondialdehyde Tetramethyl Acetal; Propane, 1,1,3,3-tetramethoxy-; TMP; MDA Bis(dimethyl acetal); 2,2'-(Methylenedioxy)bis(1,3-dioxolane)
EINECS	224-548-1

Quality Control

Our 2,2'-Methylenebis[1,3-Dioxolane] is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including GC/HPLC analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring reliable and reproducible performance in critical syntheses.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat sources and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.410 - 1.415
Density (g/mL at 20°C)	1.05 - 1.10

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.