Description

4-Formylmorpholine is a versatile and highly reactive chemical intermediate, primarily valued for its formyl group and morpholine ring structure. This compound is essential for facilitating complex organic syntheses, offering a balance of reactivity and stability for demanding industrial processes. It is a critical building block for manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop advanced active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing morpholine or formamide functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where it acts as a formylating agent.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the manufacture of specialty polymers and resins with tailored properties.
• Organic Synthesis Reagent: Employed as a formyl donor in Vilsmeier-Haack and other formylation reactions to introduce aldehyde groups into aromatic and heterocyclic compounds.
• Corrosion Inhibitor Formulation: A component in formulations designed to protect metal surfaces in industrial cooling and processing systems.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and colorants.

Basic Information

Product Name	4-Formylmorpholine
CAS No.	4394-85-8
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	4-Morpholinecarboxaldehyde; Morpholine-4-carbaldehyde; N-Formylmorpholine; 4-Formyl morpholine; N-(Formyl)morpholine; 4-Carboxaldehydemorpholine; 1-Formylmorpholine; 4-Morpholinaldehyde
EINECS	224-518-5

Quality Control

Our 4-Formylmorpholine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Every lot is subjected to comprehensive analytical testing, including assay, identity confirmation, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications. We support customer audits and can provide material for qualification against pharmaceutical (ICH Q7) or industrial grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its properties of being easily oxidized and highly volatile, it is recommended to store under an inert atmosphere (e.g., nitrogen) when in partially filled containers and at temperatures between 2°C and 25°C. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total
Refractive Index (20°C)	1.470 - 1.480
Density (20°C)	1.140 - 1.160 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.