Description

Propiophenone, 2-Amino-3-Fluoro-4-Methoxy- (7Ci,8Ci) is a specialized fluorinated aromatic ketone derivative, serving as a high-value synthetic intermediate. Its molecular structure, featuring amino, fluoro, and methoxy substituents, makes it a critical building block for constructing complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients. The CAS number for this compound is 4394-65-4.

Application

This fluorinated propiophenone derivative is a versatile intermediate designed for advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity, stability, and metabolic properties.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for advanced functional materials, including components for electronic displays and organic light-emitting diodes (OLEDs).
• Chemical Biology & Proteomics: Employed as a scaffold or tagging reagent in the design of molecular probes and activity-based protein profiling (ABPP) agents.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological development and exploratory synthesis of novel chemical entities.

Basic Information

Product Name	Propiophenone, 2-Amino-3-Fluoro-4-Methoxy- (7Ci,8Ci)
CAS No.	4394-65-4
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	2-Amino-3-fluoro-4-methoxypropiophenone; 1-(2-Amino-3-fluoro-4-methoxyphenyl)propan-1-one; 3-Fluoro-2-amino-4-methoxypropiophenone; 2-Amino-3-fluoro-4-methoxy-1-phenylpropan-1-one; Propiophenone, 2-amino-3-fluoro-4-methoxy-; 4394-65-4; 2-Amino-3-fluoro-4-methoxypropiophenone (7CI,8CI)
EINECS	Contact for details

Quality Control

Our Propiophenone, 2-Amino-3-Fluoro-4-Methoxy- (7Ci,8Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing identity, purity, and impurity profiles. Our quality management system supports compliance with relevant standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.