Description

2-Iodobenzonitrile is a versatile halogenated aromatic nitrile compound that serves as a key synthetic intermediate in advanced organic chemistry. Its value lies in the strategic combination of an iodine substituent, which is an excellent leaving group for cross-coupling reactions, and a cyano group, which can be further transformed into various functional moieties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, enabling the efficient construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heteroaryl structures via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the iodine atom facilitates the introduction of complex side chains.
• Ligand and Catalyst Precursor: Employed in the preparation of specialized ligands for catalysis and as a starting material for synthesizing metal-organic frameworks (MOFs) or other functional materials.
• Organic Electronic Materials: Serves as a precursor in the development of organic semiconductors, light-emitting diodes (OLEDs), and other advanced electronic materials due to its modifiable aromatic core.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for methodology development, exploring new reaction pathways, and synthesizing novel chemical entities for screening.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes, pigments, and imaging agents where the cyano group contributes to color and stability properties.

Basic Information

Product Name	2-Iodobenzonitrile
CAS No.	4387-36-4
Molecular Formula	C7H4IN
Molecular Weight	229.02 g/mol
Synonyms	2-Cyanoiodobenzene; o-Iodobenzonitrile; Benzonitrile, 2-iodo-; 2-Iodophenyl cyanide; 1-Iodo-2-cyanobenzene; (2-Iodophenyl)carbonitrile; 2-Jodbenzonitril; AI3-15300; NSC 403697
EINECS	Contact for details

Quality Control

Our 2-Iodobenzonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.