Description

4-Phosphonobutyric Acid is a versatile organophosphorus compound featuring a phosphonic acid group, making it a valuable building block for synthesizing complex molecules and functional materials. Its primary commercial value lies in its role as a key intermediate for the development of pharmaceuticals, agrochemicals, and specialized chelating agents. This product is essential for R&D chemists and production specialists in the pharmaceutical, agricultural chemical, and material science industries seeking to incorporate phosphonate functionality.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bisphosphonate drugs for treating bone disorders and other therapeutic agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, plant growth regulators, and fungicides with phosphonate activity.
• Ligand and Chelating Agent: Used to develop complexing agents for metal ion sequestration, catalysis, and water treatment formulations.
• Material Science: Serves as a monomer or additive for modifying polymer surfaces, creating flame retardants, and developing specialty coatings.
• Biochemical Research: Utilized as an analog of naturally occurring acids to study enzyme inhibition and metabolic pathways.
• Coordination Chemistry: Acts as a multidentate ligand for constructing metal-organic frameworks (MOFs) and other coordination polymers.

Basic Information

Product Name	4-Phosphonobutyric Acid
CAS No.	4378-43-2
Molecular Formula	C4H9O5P
Molecular Weight	168.09 g/mol
Synonyms	4-Phosphonobutanoic Acid; Butyric Acid, 4-Phosphono-; (4-Phosphonobutyl)phosphonic Acid; PBPA; NSC 25247; 4-Phosphono-Butyric Acid; γ-Phosphonobutyric Acid
EINECS	224-491-9

Quality Control

Our 4-Phosphonobutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting specifications for research and industrial use. Certificates of Analysis (COA) detailing all test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.