Description

2-Hexadecyl-Malonic Acid is a high-purity, long-chain alkyl-substituted malonic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a hydrophobic hexadecyl tail, makes it an invaluable intermediate for creating specialized surfactants, lubricant additives, and polymer modifiers. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty materials industries seeking to impart specific solubility or surface-active properties to their final products.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs requiring lipophilic character for enhanced bioavailability.
• Specialty Surfactant & Emulsifier Precursor: Acts as a key raw material for manufacturing non-ionic and anionic surfactants with tailored hydrophobic-lipophilic balance (HLB).
• Lubricant & Fuel Additive Synthesis: Employed to create polymeric viscosity modifiers and anti-wear agents that improve the performance of industrial oils and functional fluids.
• Polymer Modification: Serves as a comonomer or chain-transfer agent in polymerization reactions to alter polymer crystallinity, flexibility, and compatibility.
• Agrochemical Synthesis: Utilized in the production of herbicides and plant growth regulators where specific alkyl chain integration is required for efficacy.
• Organic Synthesis Building Block: A versatile reagent for Knoevenagel condensations and decarboxylation reactions to construct complex organic molecules.

Basic Information

Product Name	2-Hexadecyl-Malonic Acid
CAS No.	4371-64-6
Molecular Formula	C19H36O4
Molecular Weight	328.49 g/mol
Synonyms	Hexadecylmalonic Acid; 2-Hexadecylpropanedioic Acid; Palmitylmalonic Acid; Cetylmalonic Acid; 1,3-Propanedicarboxylic Acid, 2-Hexadecyl-; 2-Cetylmalonic Acid; Docosanedioic Acid, 11-Methyl- (related structure); α-Hexadecylmalonic Acid
EINECS	Contact for details

Quality Control

Our 2-Hexadecyl-Malonic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting specifications for industrial and research use. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	95 - 105 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.