Description

4-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxolane is a versatile acetal-protected chloromethylating agent, a key building block in organic synthesis. Its value lies in its ability to introduce the chloromethyl functional group under mild conditions while protecting sensitive aldehyde precursors. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct complex molecular architectures. Its application is critical for the synthesis of various active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for specialty polymers and resins.
• Fine Chemical Production: Employed in the multistep synthesis of dyes, fragrances, and other high-value specialty chemicals.
• Protecting Group Chemistry: The dioxolane moiety acts as a protective group for aldehydes during synthetic sequences.
• Material Science Research: Used in developing novel organic materials and surface modifiers.

Basic Information

Product Name	4-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxolane
CAS No.	4362-40-7
Molecular Formula	C6H11ClO2
Molecular Weight	150.60 g/mol
Synonyms	2,2-Dimethyl-4-(chloromethyl)-1,3-dioxolane; 4-Chloromethyl-2,2-dimethyl-1,3-dioxolane; Chloromethyl acetaldehyde dimethyl acetal; (Chloromethyl)acetaldehyde dimethyl acetal; Acetaldehyde, (chloromethyl)-, dimethyl acetal; NSC 403697
EINECS	224-458-5

Quality Control

Our 4-(Chloromethyl)-2,2-Dimethyl-1,3-Dioxolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.435
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.