Description

2-Oxooxolane-3-Carboxylic Acid is a versatile heterocyclic building block and chiral synthon of significant importance in fine chemical synthesis. Its unique structure, featuring both a carboxylic acid and a lactone (oxolane) moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing γ-lactone or tetrahydrofuran motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and specialty polymers requiring specific stereochemistry.
• Academic & Industrial Research: Employed in methodological development and as a model compound in organic chemistry and catalysis studies.
• Bioconjugate Chemistry: Potential use in linker chemistry for drug delivery systems due to its bifunctional reactivity.

Basic Information

Product Name	2-Oxooxolane-3-Carboxylic Acid
CAS No.	4360-91-2
Molecular Formula	C6H6O4
Molecular Weight	142.11 g/mol
Synonyms	3-Carboxy-2-oxotetrahydrofuran; 3-Carboxydihydro-2(3H)-furanone; 3-Tetrahydrofurancarboxylic acid, 2-oxo-; (S)-(-)-2-Oxo-3-tetrahydrofurancarboxylic acid (for enantiomer); 2-Oxo-3-tetrahydrofuroic acid; 3-Carboxy-2-oxooxolane; Dihydro-2-oxo-3-furancarboxylic acid; γ-Lactone of α-hydroxyglutaric acid
EINECS	224-455-3

Quality Control

Our 2-Oxooxolane-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when required for sensitive applications.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.