Description

4'-Bromoacetophenone Ethylene Acetal is a protected ketone derivative of bromoacetophenone, where the carbonyl group is masked as an acetal. This functional group protection is crucial in multi-step organic synthesis, preventing unwanted side reactions at the ketone site while allowing modifications elsewhere on the aromatic ring. It serves as a versatile and stable synthetic intermediate primarily for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over molecular architecture.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those containing substituted acetophenone or aryl ketone motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and plant growth regulators where the bromine and protected carbonyl offer specific reactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers due to its aromatic and modifiable structure.
• Fine Chemical Production: Intermediate for dyes, fragrances, and other specialty chemicals requiring selective bromination and carbonyl chemistry.

Basic Information

Product Name	4'-Bromoacetophenone Ethylene Acetal
CAS No.	4360-68-3
Molecular Formula	C10H11BrO2
Molecular Weight	243.10 g/mol
Synonyms	1-(4-Bromophenyl)-2,2-dimethyl-1,3-dioxolane; 4-Bromoacetophenone Ethylene Ketal; 2-(4-Bromophenyl)-2-methyl-1,3-dioxolane; 4-Bromo-α,α-dimethylbenzylidene Acetal; Acetophenone, 4'-bromo-, ethylene acetal; 4-Bromoacetophenone Dimethyl Acetal (common misnomer); p-Bromoacetophenone Ethylene Acetal
EINECS	Contact for details

Quality Control

Our 4'-Bromoacetophenone Ethylene Acetal is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is moisture-sensitive; ensure containers are sealed after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.