Description

Pyrrolidine, 1-(4-Fluorophenyl)- is a fluorinated heterocyclic amine building block of significant importance in modern synthetic chemistry. Its core value lies in its versatility as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials, where the introduction of a fluorinated pyrrolidine moiety can dramatically alter biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, especially in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorophenylpyrrolidine structure enhances efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Pyrrolidine, 1-(4-Fluorophenyl)-
CAS No.	4280-34-6
Molecular Formula	C10H12FN
Molecular Weight	165.21 g/mol
Synonyms	1-(4-Fluorophenyl)pyrrolidine; N-(4-Fluorophenyl)pyrrolidine; 4-Fluoro-N-pyrrolidinoaniline; 4-(Pyrrolidin-1-yl)fluorobenzene; p-Fluorophenylpyrrolidine; 4280-34-6; 1-(p-Fluorophenyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our Pyrrolidine, 1-(4-Fluorophenyl)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.