Description

3-Bromo-1,1-Dimethylcyclobutane is a versatile halogenated cyclobutane derivative, serving as a crucial building block in advanced organic synthesis. Its unique sterically hindered structure makes it valuable for introducing the dimethylcyclobutyl moiety into target molecules, enabling the exploration of novel chemical space and property modulation. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the synthesis of complex natural products.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in structure-activity relationship (SAR) studies.
• Agrochemical Research: Used in the synthesis of experimental herbicides, fungicides, and plant growth regulators that incorporate cyclobutane rings.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialized polymers with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the preparation of sterically demanding ligands for asymmetric catalysis and organometallic chemistry.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules to study biological pathways and protein interactions.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing unique musk or woody odorants due to its constrained cyclic structure.

Basic Information

Product Name	3-Bromo-1,1-Dimethylcyclobutane
CAS No.	4237-75-6
Molecular Formula	C6H11Br
Molecular Weight	163.06 g/mol
Synonyms	1,1-Dimethyl-3-bromocyclobutane; 3-Bromo-1,1-dimethyl-cyclobutane; Cyclobutane, 3-bromo-1,1-dimethyl-; NSC 163087
EINECS	Contact for details

Quality Control

Our 3-Bromo-1,1-Dimethylcyclobutane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical quality attributes. Our commitment to reliable supply and traceability supports your R&D and scale-up processes with confidence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its highly volatile nature, ensure containers are properly sealed and stored upright.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.30 g/cm³
Refractive Index (n20D)	~1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.