Description

(1R,4Aα,αr)-2,5,5,8Aβ,α-Pentamethyl-2α,α-Dihydroxydecalin-1β-Butyric Acid is a high-purity, complex decalin derivative with significant utility in advanced organic synthesis. This compound matters as a sophisticated chiral building block and intermediate for the development of novel pharmaceuticals, agrochemicals, and specialty fragrances. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and flavor & fragrance industries seeking to introduce specific stereochemistry and functional groups into target molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for steroids and terpenoid-based therapeutics.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex molecular architectures in custom synthesis and process chemistry.
• Agrochemical Research: Acts as an intermediate in developing novel pesticides and herbicides that leverage its unique decalin core structure.
• Flavor & Fragrance Industry: Employed in the synthesis of high-value aroma chemicals and musk analogs due to its stable, polycyclic framework.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or optical properties.
• Academic & R&D Laboratories: Utilized as a reference standard and starting material in methodological development and stereochemical studies.

Basic Information

Product Name	(1R,4Aα,αr)-2,5,5,8Aβ,α-Pentamethyl-2α,α-Dihydroxydecalin-1β-Butyric Acid
CAS No.	4176-94-7
Molecular Formula	C19H34O4
Molecular Weight	326.48 g/mol
Synonyms	2,5,5,8a-Tetramethyl-1,2,3,4,4a,5,6,7,8,8a-decahydro-1-naphthalenebutanoic acid, 1,4a-dihydroxy-2,5,5,8a-tetramethyl-, (1R,4aR,8aS)-rel-; (1R,4aR,8aS)-1,4a-Dihydroxy-2,5,5,8a-tetramethyl-decahydro-naphthalene-1-butanoic acid; Decalin-1-butanoic acid derivative; 4176-94-7; Pentamethyl dihydroxydecalin butyric acid
EINECS	Contact for details

Quality Control

Our (1R,4Aα,αr)-2,5,5,8Aβ,α-Pentamethyl-2α,α-Dihydroxydecalin-1β-Butyric Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.