Description

1,2,3,4,6-Penta-o-Acetyl-α-D-Mannopyranose is a key acetylated monosaccharide derivative, serving as a crucial protected intermediate in synthetic carbohydrate chemistry. Its primary value lies in enabling the controlled synthesis of complex oligosaccharides and glycoconjugates, which are essential for pharmaceutical and biochemical research. This high-purity building block is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors developing novel therapeutics, vaccines, and molecular probes.

Application

• Glycosylation Reagent: A vital protected mannose donor for the stereoselective synthesis of mannose-containing oligosaccharides and glycans.
• Pharmaceutical Intermediate: Used in the research and production of antiviral drugs, anticancer agents, and other bioactive glycoconjugates.
• Carbohydrate Chemistry Research: Serves as a standard starting material for studying glycosylation mechanisms and developing new synthetic methodologies.
• Glycoprotein & Glycolipid Synthesis: A fundamental building block for constructing complex carbohydrate moieties found in glycoproteins and glycolipids.
• Diagnostic Reagent Production: Employed in the manufacture of carbohydrate-based diagnostic tools and biosensors.
• Bioconjugation: Used to introduce mannose residues onto proteins, peptides, or other molecules for targeted drug delivery and immunology studies.

Basic Information

Product Name	1,2,3,4,6-Penta-o-Acetyl-α-D-Mannopyranose
CAS No.	4163-65-9
Molecular Formula	C16H22O11
Molecular Weight	390.34 g/mol
Synonyms	Penta-O-acetyl-α-D-mannopyranose; α-D-Mannopyranose, 1,2,3,4,6-pentaacetate; 1,2,3,4,6-Penta-O-acetyl-α-D-mannose; Acetylated α-D-Mannose; Pentaacetylmannose; α-D-Mannose pentaacetate; PAM; 4163-65-9
EINECS	224-025-9

Quality Control

Our 1,2,3,4,6-Penta-o-Acetyl-α-D-Mannopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	+49.0° to +53.0° (c=1 in CHCl3)
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.