Description

3-Trifluoromethyl-Pentanedioic Acid is a high-value fluorinated dicarboxylic acid building block, essential for introducing the trifluoromethyl group into complex molecular architectures. This compound is critical for researchers and manufacturers seeking to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. It is primarily utilized in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and metal-organic frameworks (MOFs) used in catalysis and material science.
• Fluorinated Polymer Chemistry: A monomer for producing specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Organic Synthesis Building Block: Employed in medicinal and combinatorial chemistry for the preparation of diverse compound libraries for screening.
• Advanced Material Research: Used in the development of fluorinated liquid crystals, electrolytes for batteries, and other high-performance materials.

Basic Information

Product Name	3-Trifluoromethyl-Pentanedioic Acid
CAS No.	4162-55-4
Molecular Formula	C6H7F3O4
Molecular Weight	200.11 g/mol
Synonyms	3-(Trifluoromethyl)glutaric Acid; 3-(Trifluoromethyl)pentanedioic Acid; Glutaric Acid, 3-(Trifluoromethyl)-; 3-Carboxy-4,4,4-trifluorobutyric Acid; 3-Trifluoromethylglutaric Acid; TFGA; 4162-55-4; 3-Trifluoromethyl-1,5-pentanedioic Acid
EINECS	224-025-7

Quality Control

Our 3-Trifluoromethyl-Pentanedioic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.