Description

cis-2-Phenyl-1,3-dioxan-5-ol is a versatile chiral building block and protected diol derivative, valued for its role in asymmetric synthesis and pharmaceutical intermediate manufacturing. Its unique structure, featuring a rigid dioxane ring with a phenyl substituent, provides a valuable scaffold for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity intermediates for advanced synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Asymmetric Catalyst Ligand Precursor: Used to develop and synthesize novel chiral ligands for transition metal catalysis in enantioselective reactions.
• Fine Chemical Synthesis: Serves as a protected diol unit in the multi-step synthesis of complex natural products, fragrances, and specialty chemicals.
• Agrochemical Research: Employed as a building block for creating novel chiral compounds with potential herbicidal or insecticidal activity.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, particularly in studies of stereocontrol and ring-opening reactions.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers with specific thermal or optical properties.

Basic Information

Product Name	cis-2-Phenyl-1,3-dioxan-5-ol
CAS No.	4141-19-9
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	5-Hydroxy-2-phenyl-1,3-dioxane (cis-); (5R)-2-Phenyl-1,3-dioxan-5-ol; (5S)-2-Phenyl-1,3-dioxan-5-ol; cis-5-Hydroxy-2-phenyl-m-dioxane; Phenyl-1,3-dioxan-5-ol; 2-Phenyl-5-hydroxy-1,3-dioxane; 1,3-Dioxan-5-ol, 2-phenyl-, cis-
EINECS	Contact for details

Quality Control

Every batch of cis-2-Phenyl-1,3-dioxan-5-ol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.