Description

1,2-o-Isopropylidene-3-Benzoyloxy-5,6-Dideoxy-Glucofuranose is a key protected carbohydrate intermediate, specifically a benzoylated derivative of a dideoxy sugar. This compound is valued for its role as a versatile chiral building block in sophisticated organic synthesis, enabling the controlled introduction of specific stereochemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other bioactive molecules where precise sugar modifications are critical.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of modified nucleosides and nucleotide analogs with potential antiviral or anticancer activity.
• Chiral Building Block: Used in asymmetric synthesis to construct complex natural products and drug candidates, leveraging its defined stereocenters.
• Glycochemistry Research: Serves as a protected sugar derivative for studying glycosylation reactions and synthesizing complex carbohydrate structures.
• Pro-drug Development: Utilized in the design of pro-drugs where the benzoyl group can be used for targeted release or to improve pharmacokinetic properties.
• Chemical Biology Tool: Employed in the synthesis of labeled sugars or molecular probes for investigating biological pathways.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis services catering to the agrochemical and advanced material sectors.

Basic Information

Product Name	1,2-o-Isopropylidene-3-Benzoyloxy-5,6-Dideoxy-Glucofuranose
CAS No.	4105-61-7
Molecular Formula	C₁₆H₁₈O₆
Molecular Weight	306.31 g/mol
Synonyms	3-O-Benzoyl-1,2-O-isopropylidene-5,6-dideoxy-α-D-glucofuranose; 1,2-O-Isopropylidene-3-O-benzoyl-5,6-dideoxy-α-D-glucofuranose; 3-Benzoyloxy-1,2-O-isopropylidene-5,6-dideoxy-α-D-glucofuranose; 5,6-Dideoxy-1,2-O-isopropylidene-3-O-benzoyl-α-D-glucofuranose; 1,2-O-Isopropylidene-3-benzoyloxy-5,6-dideoxy-α-D-glucofuranose; 3-O-Benzoyl-1,2:5,6-di-O-isopropylidene-α-D-glucofuranose derivative (related); Benzoylated isopropylidene glucofuranose derivative
EINECS	Contact for details

Quality Control

Our 1,2-o-Isopropylidene-3-Benzoyloxy-5,6-Dideoxy-Glucofuranose is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and pharmaceutical development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.