Description

2-Chloro-5,5-Dimethyl-1,3,2-Dioxaphosphorinan-2-One is a specialized organophosphorus compound that serves as a versatile chemical intermediate. Its value lies in its unique cyclic structure and reactive chloro group, which make it a key building block for synthesizing more complex molecules. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing phosphorus heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where its phosphorus-oxygen ring structure imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphite and phosphonate ligands used in homogeneous catalysis.
• Flame Retardant Synthon: Acts as a reactive intermediate in the manufacture of phosphorus-based flame retardants for polymers and textiles.
• Material Science Research: Employed in the development of new polymeric materials and coatings with tailored properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzymatic processes and signal transduction.

Basic Information

Product Name	2-Chloro-5,5-Dimethyl-1,3,2-Dioxaphosphorinan-2-One
CAS No.	4090-55-5
Molecular Formula	C5H10ClO3P
Molecular Weight	184.56 g/mol
Synonyms	2-Chloro-2-oxo-5,5-dimethyl-1,3,2-dioxaphosphorinane; 5,5-Dimethyl-2-chloro-1,3,2-dioxaphosphorinan-2-one; NSC 241280; 2-Chloro-5,5-dimethyl-2-oxo-1,3,2-dioxaphosphorinane; Cyclic Chlorophosphite Ester; 2-Chloro-4,4-dimethyl-1,3,2-dioxaphosphorinan-2-one (alternative numbering)
EINECS	223-847-9

Quality Control

Our 2-Chloro-5,5-Dimethyl-1,3,2-Dioxaphosphorinan-2-One is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.