Description

3-Bromo-5-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective further functionalization, making it a critical intermediate in the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for creating active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those with halogenated aromatic cores for enhanced bioactivity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and bromine atoms for efficacy.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to construct complex molecular architectures.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry in both academic and industrial R&D laboratories.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester
CAS No.	4068-73-9
Molecular Formula	C8H6BrFO3
Molecular Weight	249.04 g/mol
Synonyms	Methyl 3-Bromo-5-Fluoro-2-Hydroxybenzoate; 3-Bromo-5-Fluoro-2-Hydroxybenzoic Acid Methyl Ester; 2-Hydroxy-3-bromo-5-fluorobenzoic Acid Methyl Ester; Methyl 3-Bromo-5-Fluorosalicylate; 3-Bromo-5-Fluorosalicylic Acid Methyl Ester; Methyl 2-Hydroxy-3-bromo-5-fluorobenzoate; 3-Bromo-5-fluoro-2-hydroxy-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-2-Hydroxy-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.