Description

5-Phenyl-3-(Trifluoromethyl)Pyrazole is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the pyrazole scaffold with phenyl and trifluoromethyl substituents, which imparts desirable physicochemical properties for modulating biological activity and material characteristics. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting inflammation, central nervous system disorders, and metabolic diseases.
• Agrochemical Active Ingredient Precursor: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Ligand in Catalysis: Serves as a precursor for N-heterocyclic carbene (NHC) ligands or other coordinating frameworks used in transition metal catalysis for cross-coupling reactions.
• Material Science Research: Investigated as a building block for organic electronic materials, such as OLEDs or semiconductors, due to its conjugated system and electron-withdrawing trifluoromethyl group.
• Chemical Biology Probe Development: Utilized in medicinal chemistry to create tool compounds for studying enzyme function and protein-ligand interactions.

Basic Information

Product Name	5-Phenyl-3-(Trifluoromethyl)Pyrazole
CAS No.	4027-54-7
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	3-(Trifluoromethyl)-5-phenyl-1H-pyrazole; 5-Phenyl-3-trifluoromethylpyrazole; 1H-Pyrazole, 3-(trifluoromethyl)-5-phenyl-; 5-Phenyl-3-(trifluoromethyl)-1H-pyrazole; 4027-54-7; 3-Trifluoromethyl-5-phenylpyrazole
EINECS	Contact for details

Quality Control

Our 5-Phenyl-3-(Trifluoromethyl)Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.