Description

(E)-4-Hydroxybut-2-Enoic Acid is a high-purity, unsaturated hydroxy acid with significant utility as a versatile chemical intermediate. Its bifunctional structure, featuring both a carboxylic acid and a hydroxyl group separated by an alkene, makes it a valuable building block for synthesizing more complex molecules. This compound is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a functionalized butenoic acid backbone.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, where its reactive sites allow for the introduction of specific biological activity.
• Polymer & Material Science: Serves as a monomer or co-monomer for creating specialty polyesters, polyamides, and other functional polymers with tailored properties.
• Fine Chemical Production: An essential precursor in the manufacture of flavors, fragrances, and other high-value specialty chemicals.
• Biochemical Research: Employed as a substrate or intermediate in enzymatic studies and metabolic pathway research.
• Cross-Coupling Reactions: The alkene functionality makes it suitable for use in palladium-catalyzed cross-coupling reactions to construct complex organic frameworks.

Basic Information

Product Name	(E)-4-Hydroxybut-2-Enoic Acid
CAS No.	4013-24-5
Molecular Formula	C4H6O3
Molecular Weight	102.09 g/mol
Synonyms	(E)-4-Hydroxy-2-butenoic Acid; trans-4-Hydroxy-2-butenoic Acid; (2E)-4-Hydroxybut-2-enoic Acid; 4-Hydroxy-trans-2-butenoic Acid; 4-Hydroxycrotonic Acid; Crotonic acid, 4-hydroxy-; 2-Butenoic acid, 4-hydroxy-, (2E)-
EINECS	Contact for details

Quality Control

Every batch of (E)-4-Hydroxybut-2-Enoic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets your specific requirements for purity and consistency. A Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is supplied with each shipment, and custom specifications can be developed to align with cGMP or other regulatory standards as needed.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 99.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.