Description

(Dichlorofluoromethyl)Benzene is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both chlorine and fluorine substituents on a benzylic carbon, makes it a valuable precursor for introducing the (dichlorofluoromethyl)phenyl moiety into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the difluoromethyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Specialty Polymer Monomer: Employed in the development of high-performance, fluorinated polymers with unique chemical resistance and thermal properties.
• Organic Synthesis Reagent: Acts as an electrophile or a coupling partner in various cross-coupling and nucleophilic substitution reactions to construct complex molecular architectures.
• Chemical Research & Development: Essential reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	(Dichlorofluoromethyl)Benzene
CAS No.	498-67-9
Molecular Formula	C7H5Cl2F
Molecular Weight	179.02 g/mol
Synonyms	α,α-Dichloro-α-fluorotoluene; Benzylidene Chloride Fluoride; (Dichlorofluoromethyl)benzene; Fluorodichloromethylbenzene; Benzotrichloride, fluoro-; Phenyl(dichloro)fluoromethane; Fluorobenzal Chloride; 1-(Dichlorofluoromethyl)benzene
EINECS	207-874-1

Quality Control

Our (Dichlorofluoromethyl)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including purity assay and impurity profiles determined by GC and GC-MS. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and light exposure. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%
Density (at 20°C)	~1.33 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.