Description

Dl-Leucic Acid CAS NO 498-36-2 is a versatile chiral hydroxy acid, also known as α-hydroxyisocaproic acid, which serves as a key intermediate in organic synthesis and pharmaceutical manufacturing. Its value lies in its bifunctional structure, containing both a carboxylic acid and an α-hydroxy group, making it a valuable building block for producing fine chemicals, chiral ligands, and active pharmaceutical ingredients (APIs). This compound is essential for research institutions, pharmaceutical companies, and fine chemical manufacturers involved in asymmetric synthesis, flavor & fragrance development, and the production of specialized polymers.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for synthesizing active pharmaceutical ingredients (APIs), prodrugs, and diagnostic agents.
• Fine Chemical Synthesis: Used in the production of chiral ligands, catalysts, and complex organic molecules for research and industrial applications.
• Flavor and Fragrance Industry: Acts as a precursor for esters and other compounds that contribute to specific flavor profiles and aromatic notes.
• Biochemical Research: Employed in metabolic studies and as a standard or reagent in enzymatic and microbiological research.
• Cosmetic Ingredients: Utilized in the synthesis of certain skin-conditioning agents and specialty esters for personal care formulations.
• Polymer Chemistry: Serves as a monomer or co-monomer in the synthesis of specialized biodegradable or functional polymers.

Basic Information

Product Name	Dl-Leucic Acid
CAS No.	498-36-2
Molecular Formula	C6H12O3
Molecular Weight	132.16 g/mol
Synonyms	α-Hydroxyisocaproic Acid; 2-Hydroxy-4-methylvaleric Acid; (±)-2-Hydroxy-4-methylpentanoic Acid; DL-2-Hydroxy-4-methylvaleric Acid; DL-α-Hydroxyisocaproic Acid; Racemic Leucic Acid; 2-Hydroxyisocaproic Acid; Hydroxyleucine
EINECS	207-858-7

Quality Control

Our Dl-Leucic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC and titration methods, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic mixture (DL)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.