Description

(1S,6R)-7,7-Dimethylbicyclo[4.1.0]hept-3-ene-3-carboxylic acid is a high-purity, chiral bicyclic carboxylic acid derivative valued for its unique structural framework. This compound serves as a critical advanced pharmaceutical intermediate and a versatile chiral building block in organic synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a chiral scaffold or directing group in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Building block for developing new generation herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used to construct novel chiral ligands for transition metal catalysis and organocatalysts.
• Material Science: Potential monomer for creating specialized polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: Serves as a standard or starting material in methodological studies and process chemistry optimization.

Basic Information

Product Name	(1S,6R)-7,7-Dimethylbicyclo[4.1.0]hept-3-ene-3-carboxylic Acid
CAS No.	498-12-4
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(1S,6R)-3-Carboxy-7,7-dimethylbicyclo[4.1.0]hept-3-ene; (1S,6R)-3-Carene-3-carboxylic Acid; (-)-3-Carene-3-carboxylic Acid; (1S,6R)-7,7-Dimethyl-2,4-methano-2H-indene-1-carboxylic acid, 2,3,4,7-tetrahydro-; 3-Carene-3-carboxylic acid; Bicyclo[4.1.0]hept-3-ene-3-carboxylic acid, 7,7-dimethyl-, (1S,6R)-
EINECS	207-857-7

Quality Control

Every batch of our (1S,6R)-7,7-Dimethylbicyclo[4.1.0]hept-3-ene-3-carboxylic acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and chiral integrity meet the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) with specifications for assay, enantiomeric excess, and related substances is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.