Description

(2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-Dimethylamino-3-Hydroxy-6-Methyl-Oxan-2-Yl]Oxy-2-Ethyl-3-Hydroxy-3,7,9,11-Tetramethyl-1-Oxacyclodo Dec-4-Ene-6,12-Dione is a complex macrolide compound with a defined stereochemistry, recognized for its potent biological activity. This compound is of significant interest in advanced pharmaceutical research and development, particularly for its role as a key intermediate or active pharmaceutical ingredient (API). It is essential for researchers and manufacturers in the life sciences sector who require high-purity, structurally defined molecules for drug discovery, process development, and analytical standards.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel therapeutic agents, particularly antibiotics and anti-infectives.
• Active Pharmaceutical Ingredient (API) Development: Used in research for developing new drug formulations targeting specific bacterial pathways.
• Biochemical Research: Employed as a standard or probe in microbiological and enzymatic studies to investigate mechanism of action.
• Reference Standard: Provides a high-purity benchmark for quality control and analytical method development in pharmaceutical laboratories.
• Process Chemistry: Utilized in scaling up synthetic routes and optimizing production processes for complex macrolides.

Basic Information

Item	Detail
Product Name	(2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-Dimethylamino-3-Hydroxy-6-Methyl-Oxan-2-Yl]Oxy-2-Ethyl-3-Hydroxy-3,7,9,11-Tetramethyl-1-Oxacyclodo Dec-4-Ene-6,12-Dione
CAS No.	497-72-3
Molecular Formula	C28H47NO9
Molecular Weight	541.68 g/mol
Synonyms	Erythromycin A; Erythromycin; Erythromycin Base; Ilotycin; EM; Abomacetin; Erythrocin; E-Mycin; (8S,9S,10R,11R,12S,13R)-11-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-1-oxacyclotetradecane-6,12-dione
EINECS	207-850-3

Quality Control

Our (2R,3S,7R,9S,10S,11R)-10-[(2S,3R,4S,6R)-4-Dimethylamino-3-Hydroxy-6-Methyl-Oxan-2-Yl]Oxy-2-Ethyl-3-Hydroxy-3,7,9,11-Tetramethyl-1-Oxacyclodo Dec-4-Ene-6,12-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific USP, EP, or in-house pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	-71° to -78° (c=2, in ethanol)
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.