Description

Disalicylide is a high-purity organic compound, also known as salicylide, with the CAS registry number 486-58-8. This versatile chemical intermediate is valued for its unique cyclic dimer structure derived from salicylic acid, offering a stable platform for advanced synthesis. It is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable building blocks for complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring salicylate-derived pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators, leveraging its phenolic functionality.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal stability and specific degradation profiles.
• Organic Synthesis Building Block: Employed in research and development for constructing complex heterocyclic compounds and macrocycles.
• Cosmetic & Personal Care Ingredients: Potential intermediate for UV absorbers or preservative systems due to its structural relationship to salicylic acid.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of certain azo dyes and colorants.

Basic Information

Product Name	Disalicylide
CAS No.	486-58-8
Molecular Formula	C14H10O4
Molecular Weight	242.23 g/mol
Synonyms	Salicylide; 2,2'-Dihydroxybenzilide; 3,4-Dihydro-3,4-dioxo-1H-2-benzopyran-1-one, Dimer; Cyclic Dimer of Salicylic Acid; 1,3-Dihydro-1,3-dioxo-2H-isobenzofuran-2-spiro-1'-(3'H)-isobenzofuran-3'-one; 2-Carboxyphenyl 2-carboxyphenolate cyclic anhydride; Bis(salicyl) anhydride
EINECS	207-634-5

Quality Control

Our Disalicylide is produced under a stringent quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting specifications for industrial and research use. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	223 - 228 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.