Description

Chenodeoxycholic Acid is a primary bile acid naturally produced in the liver and a key intermediate in the synthesis of ursodeoxycholic acid. This compound is of significant commercial and research interest due to its role in cholesterol metabolism and its therapeutic applications. It is essential for manufacturers and researchers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for developing treatments for cholesterol gallstones and certain liver disorders. Chenodeoxycholic Acid CAS NO 474-25-9 is available in various high-purity grades to meet stringent industry requirements.

Application

• Pharmaceutical Active Ingredient: Key starting material and intermediate in the synthesis of ursodeoxycholic acid (UDCA), a primary therapy for dissolving cholesterol gallstones and treating primary biliary cholangitis.
• Biochemical Research: Used as a critical standard and reagent in studies of bile acid metabolism, liver function, and nuclear receptor signaling (e.g., FXR receptor activation).
• Cell Culture & Diagnostics: Employed in specialized cell culture media and as a component in diagnostic kits for liver function and metabolic disorder testing.
• Reference Standard: Serves as a high-purity certified reference material (CRM) for quality control in pharmaceutical manufacturing and analytical laboratories.
• Fine Chemical Synthesis: A versatile chiral building block for the synthesis of more complex steroid derivatives and other bioactive molecules.

Basic Information

Product Name	Chenodeoxycholic Acid
CAS No.	474-25-9
Molecular Formula	C24H40O4
Molecular Weight	392.57 g/mol
Synonyms	Chenodiol; 3α,7α-Dihydroxy-5β-cholan-24-oic Acid; CDCA; Anthropodesoxycholic Acid; Chenic Acid; Cholac; Chenofalk; Chenossil; Gallodesoxycholic Acid
EINECS	207-481-8

Quality Control

Our Chenodeoxycholic Acid is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identification by IR and melting point, and specific tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment. Production can be aligned with cGMP guidelines and relevant pharmacopoeial standards (e.g., USP, EP) for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Melting Point	165°C - 175°C
Assay (HPLC)	≥ 98.0%
Specific Rotation	+11.0° to +13.0° (c=1, in Ethanol)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.