Description

(6R)-6-[(3R,5S,7R,10S,13R)-3,7-Dihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]-2-Methylheptanoic Acid is a high-purity sterol derivative, a key intermediate in the synthesis of complex bioactive molecules. Its precise stereochemistry and defined structure make it an essential building block for research and development in advanced pharmaceutical chemistry. This compound is primarily utilized by R&D chemists and process development scientists working on novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used as a reference standard and a starting material for investigating new synthetic pathways in medicinal chemistry.
• Process Chemistry: Serves as a key chiral intermediate for scaling up the production of target active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies related to sterol metabolism, receptor binding, and enzyme inhibition assays.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs developing client-specific molecular entities.

Basic Information

Product Name	(6R)-6-[(3R,5S,7R,10S,13R)-3,7-Dihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]-2-Methylheptanoic Acid
CAS No.	17974-66-2
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	2-Methyl-6-[(3R,5S,7R,10S,13R,17R)-3,7-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]heptanoic acid; (6R)-2-Methyl-6-[(3R,5S,7R,10S,13R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]heptanoic acid; Sterol C27 acid derivative; 17β-(1,5-Dimethylhexyl)-estra-5-ene-3β,7β-diol-17α-carboxylic acid (related structure).
EINECS	Contact for details

Quality Control

Our (6R)-6-[(3R,5S,7R,10S,13R)-3,7-Dihydroxy-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthren-17-Yl]-2-Methylheptanoic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting standards for research and pharmaceutical use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider holding under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.