Description

Methyl 3Alpha-[(Ethoxycarbonyl)Oxy]-7,12-Dioxo-5Beta-Cholan-24-Oate is a high-purity, synthetic bile acid derivative with a defined steroid backbone. This compound is a critical intermediate in the research and development of novel pharmaceutical agents, particularly those targeting metabolic and liver-related pathways. It is essential for laboratories and manufacturers engaged in advanced organic synthesis, medicinal chemistry, and the production of reference standards for analytical purposes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents and prodrugs, especially in hepatology and gastroenterology.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC and LC-MS.
• Biochemical Research: Employed in studies investigating bile acid metabolism, receptor interactions, and related biological pathways.
• Process Development: Utilized in scaling up synthetic routes for pilot and commercial-scale pharmaceutical manufacturing.

Basic Information

Product Name	Methyl 3Alpha-[(Ethoxycarbonyl)Oxy]-7,12-Dioxo-5Beta-Cholan-24-Oate
CAS No.	21059-42-7
Molecular Formula	C29H42O8
Molecular Weight	518.64 g/mol
Synonyms	Methyl 3α-[(ethoxycarbonyl)oxy]-7,12-dioxo-5β-cholan-24-oate; 3α-[(Ethoxycarbonyl)oxy]-7,12-dioxo-5β-cholan-24-oic Acid Methyl Ester; 5β-Cholan-24-oic Acid, 3-[(ethoxycarbonyl)oxy]-7,12-dioxo-, Methyl Ester, (3α,5β)-; Methyl 3-(Ethoxycarbonyloxy)-7,12-dioxo-5β-cholan-24-oate; Deoxycholic Acid Derivative; Bile Acid Ester Intermediate.
EINECS	Contact for details

Quality Control

Our Methyl 3Alpha-[(Ethoxycarbonyl)Oxy]-7,12-Dioxo-5Beta-Cholan-24-Oate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.