Description

(2R)-1,2,3,4,4A,8Aβ-Hexahydro-α,α,4Aβ,8-Tetramethylnaphthalene-2α-Methanol is a high-purity, chiral intermediate of significant interest in advanced organic synthesis. Its defined stereochemistry and complex decalin-based structure make it a valuable building block for creating optically active compounds. This product is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), fragrances, and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Fragrance & Flavor Chemistry: Serves as a precursor in the synthesis of complex, stereochemically defined fragrance molecules and flavoring agents.
• Asymmetric Synthesis: Utilized as a building block in catalytic and stoichiometric asymmetric reactions to introduce specific stereocenters.
• Natural Product Synthesis: A valuable intermediate in the total synthesis of complex natural products containing decalin or related polycyclic frameworks.
• Material Science Research: Investigated as a monomer or precursor for creating novel polymers with specific chiral properties.
• Chemical Reference Standard: Used as a high-purity analytical standard for method development and quality control in related chemical processes.

Basic Information

Item	Detail
Product Name	(2R)-1,2,3,4,4A,8Aβ-Hexahydro-α,α,4Aβ,8-Tetramethylnaphthalene-2α-Methanol
CAS No.	473-17-6
Molecular Formula	C15H26O
Molecular Weight	222.37 g/mol
Synonyms	(2R)-2-Hydroxymethyl-1,2,3,4,4a,8a-hexahydro-α,α,4a,8-tetramethylnaphthalene; (2R)-2-Hydroxymethyl-1,2,3,4,4a,8a-hexahydro-1,1,4a,8-tetramethylnaphthalene; (2R)-Decahydro-2-hydroxy-α,α,4a,8-tetramethyl-2-naphthalenemethanol; (2R)-Decahydro-2-hydroxy-1,1,4a,8-tetramethyl-2-naphthalenemethanol; (2R)-2-Hydroxymethyl-1,2,3,4,4a,8a-hexahydro-1,1,4a,8-tetramethylnaphthalene; (2R)-2-(Hydroxymethyl)-1,2,3,4,4a,8a-hexahydro-1,1,4a,8-tetramethylnaphthalene; (2R)-2-Hydroxymethyl-1,2,3,4,4a,8a-hexahydro-α,α,4a,8-tetramethyl-naphthalin; (2R)-Hexahydro-α,α,4aβ,8-tetramethylnaphthalene-2α-methanol
EINECS	207-473-8

Quality Control

Our (2R)-1,2,3,4,4A,8Aβ-Hexahydro-α,α,4Aβ,8-Tetramethylnaphthalene-2α-Methanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.