Description

18β-Glycyrrhetinic Acid CAS NO 471-53-4 is a key bioactive triterpenoid compound derived from licorice root (Glycyrrhiza glabra). This high-purity ingredient is valued for its potent anti-inflammatory, antiviral, and skin-conditioning properties, making it a critical component in advanced formulations. It is primarily sought after by manufacturers in the pharmaceutical, cosmetic, and nutraceutical industries for developing therapeutic and personal care products.

Application

• Pharmaceutical Intermediates: Serves as a crucial starting material or active pharmaceutical ingredient (API) in the synthesis of anti-ulcer, hepatoprotective, and anti-viral medications.
• Cosmetic & Skincare Formulations: Widely used in creams, lotions, and serums for its anti-inflammatory and skin-whitening effects, helping to soothe irritation and reduce hyperpigmentation.
• Nutraceuticals & Dietary Supplements: Incorporated into supplements for its potential benefits in supporting liver health and modulating the immune system.
• Topical Dermatological Preparations: A key active in ointments and gels designed to treat conditions like eczema, psoriasis, and dermatitis.
• Oral Care Products: Used in toothpaste and mouthwash for its anti-inflammatory and antimicrobial properties to promote gum health.
• Research & Development: Employed as a standard reference compound in biochemical and pharmacological research to study triterpenoid pathways and biological activities.

Basic Information

Product Name	18β-Glycyrrhetinic Acid
CAS No.	471-53-4
Molecular Formula	C30H46O4
Molecular Weight	470.68 g/mol
Synonyms	Enoxolone; Glycyrrhetinic Acid; 18β-Glycyrrhetinic Acid; (3β,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic Acid; Uralenic Acid; Glycyrrhetic Acid; Biosone; Glycyron; Carbenoxolone Precursor
EINECS	207-444-6

Quality Control

Our 18β-Glycyrrhetinic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical testing, including HPLC, IR, and loss on drying. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.