Description

2,4-Dihydroxy-3,3-Dimethylbutanoic Acid is a valuable bifunctional organic compound, serving as a key chiral building block and intermediate in advanced chemical synthesis. Its unique structure, featuring both hydroxyl and carboxylic acid groups on a branched carbon chain, makes it essential for creating complex molecules with high stereochemical purity. This compound is particularly critical for pharmaceutical R&D, fine chemical manufacturing, and the production of specialized agrochemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for statins and other cardiovascular drugs.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex organic molecules, ligands, and catalysts in research and development.
• Agrochemical Production: Serves as an intermediate in the manufacture of advanced herbicides and plant growth regulators.
• Biochemical Research: Employed in the study of enzyme inhibitors and as a substrate analog in metabolic pathway investigations.
• Cosmetic Ingredient Synthesis: Acts as a starting material for producing certain moisturizing agents and skin-conditioning compounds.
• Polymer Chemistry: Utilized in the creation of specialty polyesters and other functional polymers due to its diol and acid functionality.

Basic Information

Product Name	2,4-Dihydroxy-3,3-Dimethylbutanoic Acid
CAS No.	470-29-1
Molecular Formula	C6H12O4
Molecular Weight	148.16 g/mol
Synonyms	Pantoyl Lactone; D-Pantolactone; (R)-(-)-Pantolactone; 2-Hydroxy-3,3-dimethyl-γ-butyrolactone; 3-Hydroxy-4,4-dimethyl-dihydrofuran-2(3H)-one; D-(-)-Pantolactone; (R)-Pantolactone; 2,4-Dihydroxy-3,3-dimethylbutyric Acid
EINECS	207-424-3

Quality Control

Our 2,4-Dihydroxy-3,3-Dimethylbutanoic Acid is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay and impurity profile analysis, to ensure it meets the stringent requirements of our global customer base. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and specific tests are provided with every shipment. We can supply material compliant with various pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	90°C - 94°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.