Description

(-)-Drimenol is a naturally occurring sesquiterpene alcohol, a key chiral intermediate and building block in organic synthesis. Its defined stereochemistry and functional group make it a valuable starting material for the synthesis of complex natural products and bioactive compounds. This high-purity material is essential for research and development in the pharmaceutical, agrochemical, and fragrance industries, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Serves as a chiral precursor for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators with specific stereochemical requirements.
• Fragrance & Flavor Chemistry: Acts as a starting material for creating unique, natural-identical sesquiterpenoid aroma compounds.
• Natural Product Research: A standard and building block for the total synthesis of drimane-type sesquiterpenoids found in plants and fungi.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Asymmetric Catalysis: Employed as a substrate or ligand precursor in the development of stereoselective catalytic reactions.

Basic Information

Product Name	(-)-Drimenol
CAS No.	468-68-8
Molecular Formula	C15H26O
Molecular Weight	222.37 g/mol
Synonyms	(-)-Drimenol; (1S,4aS,8aS)-1,4a-Dimethyl-7-methylidene-2,3,4,5,6,8a-hexahydro-1H-naphthalen-1-ol; Drimenol; Drimenol, (-)-; Drimenol, (1S,4aS,8aS)-; (1S,4aS,8aS)-1,4a-Dimethyl-7-methylene-decahydronaphthalen-1-ol; NSC 163990
EINECS	207-416-6

Quality Control

Our (-)-Drimenol is produced and tested under a strict quality management system. Each batch is analyzed to ensure high chemical and chiral purity, meeting the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), optical rotation, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Specific Optical Rotation	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.