Description

Rehmannic Acid CAS NO 467-81-2 is a bioactive phytochemical compound derived from the roots of *Rehmannia glutinosa*, a plant widely used in traditional medicine. This compound is valued for its role as a key chemical marker and active ingredient in the standardization of herbal extracts and nutraceutical formulations. It is primarily sought by manufacturers in the pharmaceutical, dietary supplement, and cosmetic industries for research, development, and quality control of products leveraging the therapeutic properties of Rehmannia.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of Rehmannia-based drugs and extracts in pharmacopoeial methods.
• Nutraceutical & Dietary Supplements: Serves as a bioactive marker for the standardization and quality assurance of herbal supplements claiming benefits for kidney and liver health.
• Cosmetic & Skincare Actives: Incorporated into formulations for its purported anti-inflammatory and moisturizing properties, often found in products targeting skin vitality and anti-aging.
• Biomedical & Clinical Research: Utilized in *in vitro* and *in vivo* studies to investigate its pharmacological activities, including potential effects on metabolism and immune modulation.
• Traditional Medicine Product Development: Acts as a critical quality control parameter in the modernization and global commercialization of standardized Traditional Chinese Medicine (TCM) products.
• Analytical Chemistry: Employed by testing laboratories as an analytical standard for method development and validation in HPLC, LC-MS, and TLC analyses.

Basic Information

Item	Details
Product Name	Rehmannic Acid
CAS No.	467-81-2
Molecular Formula	C16H22O8
Molecular Weight	342.34 g/mol
Synonyms	Rehmannic acid; 3,4-Dihydroxybenzoic acid 4-β-D-glucopyranoside; Catalposide aglycone derivative; Rehmannia acid; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[2-(3,4-dihydroxyphenyl)ethoxy]oxane-3,4,5-triol (related IUPAC); Rehmannia glutinosa active ingredient
EINECS	Contact for details

Quality Control

Our Rehmannic Acid is produced and controlled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support compliance with relevant pharmacopoeial guidelines for herbal reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.