Description

Hederagenin is a pentacyclic triterpenoid compound, a key aglycone derived from saponins found in plants like ivy (*Hedera helix*). This compound matters for its significant bioactivity, serving as a crucial intermediate and reference standard in pharmaceutical and nutraceutical research. Industries that need it include pharmaceutical R&D for anti-inflammatory and hepatoprotective agent development, as well as manufacturers of high-purity botanical extracts and dietary supplements.

Application

• Pharmaceutical Intermediate: Serves as a key starting material or reference standard in the synthesis and quality control of triterpenoid-based drugs.
• Reference Standard: Used in analytical laboratories for the identification and quantification of saponins in herbal extracts via HPLC or LC-MS methods.
• Nutraceutical & Cosmetic Ingredient: Incorporated into formulations for its purported anti-inflammatory, antioxidant, and skin-conditioning properties.
• Biomedical Research: Employed in *in vitro* and *in vivo* studies to investigate mechanisms related to apoptosis, inflammation, and metabolic pathways.
• Botanical Extract Standardization: Acts as a marker compound to standardize and ensure the potency and consistency of ivy and other saponin-rich extracts.
• Chemical Synthesis: Utilized as a versatile scaffold for the semi-synthesis of novel triterpenoid derivatives with enhanced biological activity.

Basic Information

Product Name	Hederagenin
CAS No.	465-99-6
Molecular Formula	C30H48O4
Molecular Weight	472.70 g/mol
Synonyms	Hederagenin; 3β,23-Dihydroxyolean-12-en-28-oic acid; Olean-12-ene-28-oic acid, 3,23-dihydroxy-, (3β)-; Hedergenin; Kalopanaxsaponin A aglycone; α-Hederin aglycone; Hederagenine; Hedera-genin
EINECS	207-366-5

Quality Control

Our Hederagenin is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets high-grade specifications suitable for research and development. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.