Description

9-Fluoro-1-Nonyne is a versatile fluorinated alkyne building block, distinguished by its terminal alkyne and fluorine substituent. This unique structure makes it a valuable intermediate for introducing both fluorine atoms and alkyne functional groups into more complex molecules, enabling advanced material synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in click chemistry, cross-coupling reactions, and the development of novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of fluorinated drug candidates, leveraging the metabolic stability and lipophilicity imparted by the fluorine atom.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the fluorine moiety can enhance biological activity and environmental persistence.
• Click Chemistry Reagent: The terminal alkyne group participates efficiently in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Material Science: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic semiconductors to modify electronic properties and surface characteristics.
• Cross-Coupling Reactions: Acts as a coupling partner in Sonogashira, Heck, and other palladium-catalyzed reactions to construct complex molecular architectures.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological processes due to the bio-orthogonal nature of the alkyne handle.

Basic Information

Item	Detail
Product Name	9-Fluoro-1-Nonyne
CAS No.	463-19-4
Molecular Formula	C9H15F
Molecular Weight	142.21 g/mol
Synonyms	1-Nonyne, 9-fluoro-; 9-Fluorononyne; 9-Fluoro-1-nonyne; 9-Fluoronon-1-yne; Non-1-yn-9-yl fluoride; Fluorononyne
EINECS	Contact for details

Quality Control

Our 9-Fluoro-1-Nonyne is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles to meet your specific research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place at 2-8°C or as specified on the label. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.