Description

4-Fluorobutyraldehyde is a versatile fluorinated aldehyde building block, essential for introducing the 4-fluorobutyl moiety into complex molecules. Its primary value lies in serving as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, enabling critical carbon-fluorine bond formation. This compound is particularly sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated alkyl chain to modulate bioavailability, metabolic stability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine incorporation enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Fluorinated Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: Utilized in various organic transformations, including nucleophilic addition, reductive amination, and as a substrate for homologation reactions in research and development.
• Cross-coupling Reaction Component: Acts as an electrophile in palladium-catalyzed and other cross-coupling reactions to create complex fluorinated architectures.

Basic Information

Item	Details
Product Name	4-Fluorobutyraldehyde
CAS No.	462-74-8
Molecular Formula	C4H7FO
Molecular Weight	90.10 g/mol
Synonyms	4-Fluorobutanal; γ-Fluorobutyraldehyde; 4-Fluorobutylaldehyde; 4-Fluorobutyral; Butanal, 4-fluoro-; 1-Fluorobutanal-4; 4-Fluorobutane-1-al
EINECS	Contact for details

Quality Control

Our 4-Fluorobutyraldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C to minimize degradation. Keep away from strong oxidizing agents, bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.