Description

3-Fluoropropan-1-ol is a versatile fluorinated alcohol building block with significant utility in advanced organic synthesis. Its unique structure, featuring a terminal fluorine atom, makes it a valuable intermediate for introducing fluorinated moieties into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine substitution can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating novel herbicides, pesticides, and fungicides, leveraging fluorine's ability to improve lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved dielectric anisotropy and stability.
• Polymer Modification: Employed to introduce fluorine into polymer side chains, enhancing material properties such as solvent resistance, thermal stability, and surface characteristics.
• Proteolysis-Targeting Chimera (PROTAC) Linkers: Potential use in constructing bifunctional molecules for targeted protein degradation, a cutting-edge therapeutic modality.
• Fluorinated Surfactant & Coating Precursor: Acts as a starting material for synthesizing specialty surfactants and surface modifiers with low surface energy.

Basic Information

Product Name	3-Fluoropropan-1-ol
CAS No.	462-43-1
Molecular Formula	C3H7FO
Molecular Weight	78.08 g/mol
Synonyms	3-Fluoropropanol; 3-Fluoro-1-propanol; 3-Fluoropropyl alcohol; 1-Propanol, 3-fluoro-; 3-Fluoro-n-propanol; γ-Fluoropropanol; 3-FP; F3C3OH
EINECS	207-328-2

Quality Control

Our 3-Fluoropropan-1-ol is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support customer audits and regulatory documentation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, containers should be kept tightly sealed when not in use to prevent moisture absorption. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Refractive Index (n20D)	1.380 - 1.390
Density (g/mL at 20°C)	1.05 - 1.10

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.