Description

4-Fluorobutyraldehyde is a versatile fluorinated aldehyde building block of significant interest in advanced organic synthesis. Its value lies in its ability to introduce both fluorine and an aldehyde functional group, enabling the construction of complex molecules for pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as the synthesis of novel active ingredients and fluorinated intermediates.

Application

• Pharmaceutical Intermediate: A key starting material or building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel fluorinated pesticides, herbicides, and plant growth regulators.
• Fluorinated Fine Chemicals: Serves as a precursor for manufacturing specialized fluorinated compounds used in materials science and electronics.
• Organic Synthesis Building Block: Employed in various organic reactions, including nucleophilic additions, reductive aminations, and cyclizations, to create complex molecular architectures.
• Ligand and Catalyst Development: Useful in the preparation of fluorinated ligands for catalysis and metal-organic frameworks (MOFs).
• Life Sciences Research: Utilized as a biochemical tool or probe in medicinal chemistry and chemical biology research programs.

Basic Information

Product Name	4-Fluorobutyraldehyde
CAS No.	461-53-0
Molecular Formula	C4H7FO
Molecular Weight	90.10 g/mol
Synonyms	4-Fluorobutanal; γ-Fluorobutyraldehyde; 4-Fluorobutyral; Butanal, 4-fluoro-; 4-Fluorobutylaldehyde; 1-Fluorobutanal-4; 4-Fluorobutane-1-al
EINECS	207-320-7

Quality Control

Our 4-Fluorobutyraldehyde is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP manufacturing standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. This material is easily oxidized and should be handled with care to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.