Description

3,3-Difluoropropan-1-Amine is a versatile fluorinated amine building block of significant importance in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine atoms and a reactive primary amine group, enabling the modulation of physicochemical properties and bioactivity in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, including protease inhibitors, kinase inhibitors, and CNS-active compounds.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides where fluorine enhances metabolic stability and membrane permeability.
• Ligand and Catalyst Design: Used in the preparation of fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Serves as a monomer or cross-linking agent for introducing amine functionality and fluorinated segments into polymers, improving surface properties and chemical resistance.
• Fluorinated Surfactant & Material Precursor: Intermediate in the synthesis of fluorinated surfactants, ionic liquids, and specialty coatings.
• Bioconjugation and Probe Chemistry: Useful for modifying biomolecules or creating fluorescent probes due to its reactive amine handle and fluorinated tag.

Basic Information

Product Name	3,3-Difluoropropan-1-Amine
CAS No.	461-50-7
Molecular Formula	C3H7F2N
Molecular Weight	95.09 g/mol
Synonyms	3,3-Difluoropropylamine; 3,3-Difluoro-1-propanamine; 1-Amino-3,3-difluoropropane; 3,3-Difluoropropanamine; 3,3-Difluoropropan-1-amine; 461-50-7; 3,3-Difluoropropyl amine
EINECS	Contact for details

Quality Control

Our 3,3-Difluoropropan-1-Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. For long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen) to preserve quality. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.