Description

4,4,4-Trifluorobutyramide is a versatile fluorinated amide compound that serves as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity and stability imparted by the trifluoromethyl group, enabling the development of novel materials and active ingredients. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the introduction of fluorine atoms can significantly improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Fluorinated Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Building Block: Utilized in various name reactions and coupling chemistries to construct complex molecules for research and fine chemical production.
• Biochemical Probe Development: Acts as a precursor for creating labeled compounds and probes used in medicinal chemistry and life science research.

Basic Information

Product Name	4,4,4-Trifluorobutyramide
CAS No.	461-34-7
Molecular Formula	C₄H₆F₃NO
Molecular Weight	141.09 g/mol
Synonyms	4,4,4-Trifluorobutanamide; 4,4,4-Trifluorobutyric acid amide; Butanamide, 4,4,4-trifluoro-; NSC 92359; γ,γ,γ-Trifluorobutyramide; 4,4,4-Trifluoro-1-butanamide; 4,4,4-Trifluorobutyric Amide
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluorobutyramide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.